RAF Typhoon fighter aircraft have conducted a mission with French warplanes in a joint strike on an hidden munitions depot in Syria operated by the IS group, according to the British defence ministry.
The location, pinpointed through reconnaissance, was thought to be containing munitions and bombs, the release indicated, and was situated in mountains just north of Palmyra in the heart of Syria.
"The RAF jets utilized Paveway IV guided bombs to strike a number of approach shafts down to the depot... initial indications suggest the target was engaged successfully," officials stated.
There was no evidence of any civilian casualties in the operation on Saturday evening and all the aircraft made a safe return, the ministry further stated.
The Typhoon FGR4s were backed up by a Voyager aerial refuelling aircraft.
Daesh - alternatively referred to as the so-called Islamic State - enforced militant control over parts of Syria and Iraq until 2019.
"This operation shows the UK's leading role, and commitment to operate in unison with our allies, to stamp out any revival of IS and their dangerous and violent ideologies in the Middle East," Britain's Defence Chief John Healey said.
British military aircraft have carried out overwatch operations over Syrian airspace to "prevent any attempted resurgence" of Islamic State subsequent to its military defeat at the battle of Baghuz in 2019, the ministry said.
"I extend gratitude to all the members of British forces participating in this strike for their expertise and their bravery," he added. "Including them were a great many British troops deployed over the holidays. This mission, to remove dangerous terrorists who threaten our way of life, demonstrates how our armed forces are ready to step up, all year round, protecting the UK within its borders and influential overseas."
Last December, the US military conducted what it termed a "massive strike" targeting Islamic State objectives in the country, after an assault claimed the lives of two US troops and a civilian linguist in the Palmyra area.
The UN reports Islamic State still boasts an estimated 5,000 to 7,000 combatants in Iraq and Syria.